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Receive this page by email each issue: [Sign up for eTOCs] Other Issues: November 1 2008; 112 (9)   [Index by Author]  [Cover Caption]  [Complete Inside Blood PDF]         INSIDE BLOOD        BLOOD WORK        ASH 50TH ANNIVERSARY REVIEW        REVIEW ARTICLES        CHEMOKINES, CYTOKINES, AND INTERLEUKINS        CLINICAL TRIALS AND OBSERVATIONS        HEMATOPOIESIS AND STEM CELLS        HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY        IMMUNOBIOLOGY        NEOPLASIA        PHAGOCYTES        RED CELLS        TRANSPLANTATION        CORRESPONDENCE Find articles in this issue containing these words: [Search ALL Issues] Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) | Advertising (PDF) To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link. INSIDE BLOOD: CD40: Lord of the endothelial cell Richard P. Phipps Blood 2008 112: 3531-3532. [Full Text] [PDF]   Is more better in myeloma? Guido Tricot Blood 2008 112: 3532. [Full Text] [PDF]   MGUS: not so benign after all Michael J. Kovacs Blood 2008 112: 3533. [Full Text] [PDF]   Shear activates platelet-derived latent TGF-β Kohei Miyazono Blood 2008 112: 3533-3534. [Full Text] [PDF]   The hematopoiesis paradigm: clarity or ambiguity? Chozhavendan Rathinam and Richard A. Flavell Blood 2008 112: 3534-3535. [Full Text] [PDF]   "Vitamin hypothesis": explanation for allergy increase? Stephan C. Bischoff Blood 2008 112: 3535-3536. [Full Text] [PDF]   E-selectin prefers fatty-sweet receptors on rolling neutrophils Scott I. Simon Blood 2008 112: 3537. [Full Text] [PDF]   Suppressing the tumor suppressor in CLL? Chris Pepper Blood 2008 112: 3537-3538. [Full Text] [PDF]   Mcl-1: the 1 in CLL Varsha Gandhi, Kumudha Balakrishnan, and Lisa S. Chen Blood 2008 112: 3538-3540. [Full Text] [PDF]   Why is CLL refractory to bortezomib? Ranmohan Gitendra Wickremasinghe Blood 2008 112: 3540-3541. [Full Text] [PDF]   BLOOD WORK: Neutrophil granules Blood 2008 112: 3554. [Full Text] [PDF]   ASH 50TH ANNIVERSARY REVIEW: The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases Irving L. Weissman and Judith A. Shizuru Blood 2008 112: 3543-3553. [Abstract] [Full Text] [PDF]   REVIEW ARTICLES: Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment Guido Stoll, Christoph Kleinschnitz, and Bernhard Nieswandt Blood 2008 112: 3555-3562. Prepublished online August 1, 2008; DOI 10.1182/blood-2008-04-144758 [Abstract] [Full Text] [PDF]   CHEMOKINES, CYTOKINES, AND INTERLEUKINS: HMG-CoA reductase inhibition induces IL-1β release through Rac1/PI3K/PKB-dependent caspase-1 activation Loes M. Kuijk, Jeffrey M. Beekman, Janet Koster, Hans R. Waterham, Joost Frenkel, and Paul J. Coffer Blood 2008 112: 3563-3573. Prepublished online August 6, 2008; DOI 10.1182/blood-2008-03-144667 [Abstract] [Full Text] [PDF] [Supplemental Figures]   CLINICAL TRIALS AND OBSERVATIONS: A survey of fully haploidentical hematopoietic stem cell transplantation in adults with high-risk acute leukemia: a risk factor analysis of outcomes for patients in remission at transplantation Fabio Ciceri, Myriam Labopin, Franco Aversa, Jakob M. Rowe, Donald Bunjes, Philippe Lewalle, Arnon Nagler, Paolo Di Bartolomeo, João F. Lacerda, Maria Teresa Lupo Stanghellini, Emmanuelle Polge, Francesco Frassoni, Massimo F. Martelli, and Vanderson Rocha, on behalf of the Acute Leukemia Working Party (ALWP) of the European Blood and Marrow Transplant (EBMT) Group Blood 2008 112: 3574-3581. Prepublished online July 7, 2008; DOI 10.1182/blood-2008-02-140095 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   Deep vein thrombosis after monoclonal gammopathy of undetermined significance and multiple myeloma Sigurdur Y. Kristinsson, Thomas R. Fears, Gloria Gridley, Ingemar Turesson, Ulf-Henrik Mellqvist, Magnus Björkholm, and Ola Landgren Blood 2008 112: 3582-3586. Prepublished online June 17, 2008; DOI 10.1182/blood-2008-04-151076 [Abstract] [Full Text] [PDF]   Brief report  Determinants of cerebrospinal fluid arsenic concentration in patients with acute promyelocytic leukemia on oral arsenic trioxide therapy Wing-Yan Au, Sidney Tam, Bonnie M. Fong, and Yok-Lam Kwong Blood 2008 112: 3587-3590. Prepublished online August 14, 2008; DOI 10.1182/blood-2008-06-161000 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Brief report  A prospective PETHEMA study of tandem autologous transplantation versus autograft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma Laura Rosiñol, José Antonio Pérez-Simón, Anna Sureda, Javier de la Rubia, Felipe de Arriba, Juan José Lahuerta, José David González, Joaquín Díaz-Mediavilla, Belén Hernández, Javier García-Frade, Dolores Carrera, Angel León, Miguel Hernández, Pascual Fernández Abellán, Juan Miguel Bergua, Jesús San Miguel, and Joan Bladé, for Programa para el Estudio y la Terapéutica de las Hemopatías Malignas y Grupo Español de Mieloma (PETHEMA/GEM) Blood 2008 112: 3591-3593. Prepublished online July 8, 2008; DOI 10.1182/blood-2008-02-141598 [Abstract] [Full Text] [PDF] [Supplemental Appendix]   HEMATOPOIESIS AND STEM CELLS: TINF2 mutations result in very short telomeres: analysis of a large cohort of patients with dyskeratosis congenita and related bone marrow failure syndromes Amanda J. Walne, Tom Vulliamy, Richard Beswick, Michael Kirwan, and Inderjeet Dokal Blood 2008 112: 3594-3600. Prepublished online July 30, 2008; DOI 10.1182/blood-2008-05-153445 [Abstract] [Full Text] [PDF]   Expression of angiotensin-converting enzyme (CD143) identifies and regulates primitive hemangioblasts derived from human pluripotent stem cells Elias T. Zambidis, Tea Soon Park, Wayne Yu, Ada Tam, Michal Levine, Xuan Yuan, Marina Pryzhkova, and Bruno Péault Blood 2008 112: 3601-3614. Prepublished online August 26, 2008; DOI 10.1182/blood-2008-03-144766 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY: Low plasma levels of tissue factor pathway inhibitor in patients with congenital factor V deficiency Connie Duckers, Paolo Simioni, Luca Spiezia, Claudia Radu, Sabrina Gavasso, Jan Rosing, and Elisabetta Castoldi Blood 2008 112: 3615-3623. Prepublished online August 11, 2008; DOI 10.1182/blood-2008-06-162453 [Abstract] [Full Text] [PDF]   CD40: an upstream master switch for endothelial cell activation uncovered by RNAi-coupled transcriptional profiling Raquel Pluvinet, Rut Olivar, Jerzy Krupinski, Inmaculada Herrero-Fresneda, Anna Luque, Joan Torras, Josep M. Cruzado, Josep M. Grinyó, Lauro Sumoy, and Josep M. Aran Blood 2008 112: 3624-3637. Prepublished online July 31, 2008; DOI 10.1182/blood-2008-03-143305 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization Harukiyo Kawamura, Xiujuan Li, Katsutoshi Goishi, Laurens A. van Meeteren, Lars Jakobsson, Stéphanie Cébe-Suarez, Akio Shimizu, Dan Edholm, Kurt Ballmer-Hofer, Lena Kjellén, Michael Klagsbrun, and Lena Claesson-Welsh Blood 2008 112: 3638-3649. Prepublished online July 29, 2008; DOI 10.1182/blood-2007-12-125856 [Abstract] [Full Text] [PDF] [Supplemental Figures]   In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-β1 Jasimuddin Ahamed, Nathalie Burg, Keiji Yoshinaga, Christin A. Janczak, Daniel B. Rifkin, and Barry S. Coller Blood 2008 112: 3650-3660. Prepublished online June 10, 2008; DOI 10.1182/blood-2008-04-151753 [Abstract] [Full Text] [PDF]   IMMUNOBIOLOGY: Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response Chung-Sheng Shi, Guey-Yueh Shi, Shi-Ming Hsiao, Yuan-Chung Kao, Kuan-Lin Kuo, Chih-Yuan Ma, Cheng-Hsiang Kuo, Bi-Ing Chang, Chuan-Fa Chang, Chun-Hung Lin, Chi-Huey Wong, and Hua-Lin Wu Blood 2008 112: 3661-3670. Prepublished online August 18, 2008; DOI 10.1182/blood-2008-03-142760 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines Chun I. Yu, Michael Gallegos, Florentina Marches, Gerard Zurawski, Octavio Ramilo, Adolfo García-Sastre, Jacques Banchereau, and A. Karolina Palucka Blood 2008 112: 3671-3678. Prepublished online August 19, 2008; DOI 10.1182/blood-2008-05-157016 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]   Telomerase activity of HIV-1–specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors Mathias Lichterfeld, Danlei Mou, Thai Duong Hong Cung, Katie L. Williams, Michael T. Waring, Jinghe Huang, Florencia Pereyra, Alicja Trocha, Gordon J. Freeman, Eric S. Rosenberg, Bruce D. Walker, and Xu G. Yu Blood 2008 112: 3679-3687. Prepublished online August 26, 2008; DOI 10.1182/blood-2008-01-135442 [Abstract] [Full Text] [PDF]   Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells Lukas T. Jeker, Thomas Barthlott, Marcel P. Keller, Saulius Zuklys, Mathias Hauri-Hohl, Chu-Xia Deng, and Georg A. Holländer Blood 2008 112: 3688-3695. Prepublished online August 11, 2008; DOI 10.1182/blood-2008-04-150532 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansion Carlo Chizzolini, Rachel Chicheportiche, Montserrat Alvarez, Casimir de Rham, Pascale Roux-Lombard, Sylvie Ferrari-Lacraz, and Jean-Michel Dayer Blood 2008 112: 3696-3703. Prepublished online August 12, 2008; DOI 10.1182/blood-2008-05-155408 [Abstract] [Full Text] [PDF]   IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response Mark P. Rubinstein, Nicholas A. Lind, Jared F. Purton, Pauline Filippou, J. Adam Best, Patrick A. McGhee, Charles D. Surh, and Ananda W. Goldrath Blood 2008 112: 3704-3712. Prepublished online August 8, 2008; DOI 10.1182/blood-2008-06-160945 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation Juliette Mouriès, Gabriel Moron, Géraldine Schlecht, Nicolas Escriou, Gilles Dadaglio, and Claude Leclerc Blood 2008 112: 3713-3722. Prepublished online August 12, 2008; DOI 10.1182/blood-2008-03-146290 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Divergent effects of hypoxia on dendritic cell functions Alessandra Mancino, Tiziana Schioppa, Paola Larghi, Fabio Pasqualini, Manuela Nebuloni, I-Hsuan Chen, Silvano Sozzani, Jonathan M. Austyn, Alberto Mantovani, and Antonio Sica Blood 2008 112: 3723-3734. Prepublished online August 11, 2008; DOI 10.1182/blood-2008-02-142091 [Abstract] [Full Text] [PDF]   Neutralization of tumor-derived soluble Glucocorticoid-Induced TNFR-Related Protein ligand increases NK cell anti-tumor reactivity Katrin M. Baltz, Matthias Krusch, Tina Baessler, Benjamin J. Schmiedel, Anita Bringmann, Peter Brossart, and Helmut R. Salih Blood 2008 112: 3735-3743. Prepublished online August 8, 2008; DOI 10.1182/blood-2008-03-143016 [Abstract] [Full Text] [PDF] [Supplemental Figures]   E-selectin receptors on human leukocytes Leonardo Nimrichter, Monica M. Burdick, Kazuhiro Aoki, Wouter Laroy, Mark A. Fierro, Sherry A. Hudson, Christopher E. Von Seggern, Robert J. Cotter, Bruce S. Bochner, Michael Tiemeyer, Konstantinos Konstantopoulos, and Ronald L. Schnaar Blood 2008 112: 3744-3752. Prepublished online June 25, 2008; DOI 10.1182/blood-2008-04-149641 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection Robert S. Welner, Rosana Pelayo, Yoshinori Nagai, Karla P. Garrett, Todd R. Wuest, Daniel J. Carr, Lisa A. Borghesi, Michael A. Farrar, and Paul W. Kincade Blood 2008 112: 3753-3761. Prepublished online June 13, 2008; DOI 10.1182/blood-2008-04-151506 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Human basophils activated by mast cell–derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid Nicole Spiegl, Svetlana Didichenko, Peter McCaffery, Hanno Langen, and Clemens A. Dahinden Blood 2008 112: 3762-3771. Prepublished online May 21, 2008; DOI 10.1182/blood-2008-01-135251 [Abstract] [Full Text] [PDF] [Supplemental Methods, Tables, and Figures]   Brief report  Lack of endogenous TRIM5-mediated restriction in rhesus macaque dendritic cells Nathalie J. Arhel, Sébastien Nisole, Laetitia Carthagena, Frédéric Coutant, Philippe Souque, Audrey Brussel, Jérôme Estaquier, and Pierre Charneau Blood 2008 112: 3772-3776. Prepublished online August 14, 2008; DOI 10.1182/blood-2008-04-151761 [Abstract] [Full Text] [PDF]   NEOPLASIA: PEBP2-β/CBF-β–dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis Hee-Jun Wee, Dominic Chih-Cheng Voon, Suk-Chul Bae, and Yoshiaki Ito Blood 2008 112: 3777-3787. Prepublished online August 11, 2008; DOI 10.1182/blood-2008-01-134122 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation Joshua Arnold, Bevin Zimmerman, Min Li, Michael D. Lairmore, and Patrick L. Green Blood 2008 112: 3788-3797. Prepublished online August 8, 2008; DOI 10.1182/blood-2008-04-154286 [Abstract] [Full Text] [PDF]   IRF-4 functions as a tumor suppressor in early B-cell development Jaime Acquaviva, Xiaoren Chen, and Ruibao Ren Blood 2008 112: 3798-3806. Prepublished online August 19, 2008; DOI 10.1182/blood-2007-10-117838 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers Chris Pepper, Thet Thet Lin, Guy Pratt, Saman Hewamana, Paul Brennan, Louise Hiller, Robert Hills, Rachel Ward, Jane Starczynski, Belinda Austen, Laura Hooper, Tatjana Stankovic, and Chris Fegan Blood 2008 112: 3807-3817. Prepublished online July 3, 2008; DOI 10.1182/blood-2008-05-157131 [Abstract] [Full Text] [PDF] [Supplemental Table and Figures]   IL-4 protein expression and basal activation of Erk in vivo in follicular lymphoma Katherine R. Calvo, Bhavana Dabir, Alexandra Kovach, Christopher Devor, Russell Bandle, Amelia Bond, Joanna H. Shih, and Elaine S. Jaffe Blood 2008 112: 3818-3826. Prepublished online August 5, 2008; DOI 10.1182/blood-2008-02-138933 [Abstract] [Full Text] [PDF]   p53-mediated apoptosis of CLL cells: evidence for a transcription-independent mechanism Andrew J. Steele, Archibald G. Prentice, A. Victor Hoffbrand, Birunthini C. Yogashangary, Stephen M. Hart, Elisabeth P. Nacheva, Julie D. Howard-Reeves, Veronique M. Duke, Panagiotis D. Kottaridis, Kate Cwynarski, Lyubomir T. Vassilev, and R. Gitendra Wickremasinghe Blood 2008 112: 3827-3834. Prepublished online August 5, 2008; DOI 10.1182/blood-2008-05-156380 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib Feng-Ting Liu, Samir G. Agrawal, Zanyar Movasaghi, Peter B. Wyatt, Ihtesham U. Rehman, John G. Gribben, Adrian C. Newland, and Li Jia Blood 2008 112: 3835-3846. Prepublished online July 16, 2008; DOI 10.1182/blood-2008-04-150227 [Abstract] [Full Text] [PDF] [Supplemental Figures]   Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance Ilaria Iacobucci, Annalisa Lonetti, Francesca Messa, Daniela Cilloni, Francesca Arruga, Emanuela Ottaviani, Stefania Paolini, Cristina Papayannidis, Pier Paolo Piccaluga, Panagiota Giannoulia, Simona Soverini, Marilina Amabile, Angela Poerio, Giuseppe Saglio, Fabrizio Pane, Giorgio Berton, Anna Baruzzi, Antonella Vitale, Sabina Chiaretti, Giovanni Perini, Robin Foà, Michele Baccarani, and Giovanni Martinelli Blood 2008 112: 3847-3855. Prepublished online July 23, 2008; DOI 10.1182/blood-2007-09-112631 [Abstract] [Full Text] [PDF] [Supplemental Figure]   Kpm/Lats2 is linked to chemosensitivity of leukemic cells through the stabilization of p73 Masahiro Kawahara, Toshiyuki Hori, Kazuhisa Chonabayashi, Tsutomu Oka, Marius Sudol, and Takashi Uchiyama Blood 2008 112: 3856-3866. Prepublished online June 18, 2008; DOI 10.1182/blood-2007-09-111773 [Abstract] [Full Text] [PDF] [Supplemental Figures]   PHAGOCYTES: FcR-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome Wei Tian, Xing Jun Li, Natalie D. Stull, Wenyu Ming, Chang-Il Suh, Sarah A. Bissonnette, Michael B. Yaffe, Sergio Grinstein, Simon J. Atkinson, and Mary C. Dinauer Blood 2008 112: 3867-3877. Prepublished online August 18, 2008; DOI 10.1182/blood-2007-11-126029 [Abstract] [Full Text] [PDF] [Supplemental Figures and Videos]   RED CELLS: Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1 Marc A. Kerenyi, Florian Grebien, Helmuth Gehart, Manfred Schifrer, Matthias Artaker, Boris Kovacic, Hartmut Beug, Richard Moriggl, and Ernst W. Müllner Blood 2008 112: 3878-3888. Prepublished online August 11, 2008; DOI 10.1182/blood-2008-02-138339 [Abstract] [Full Text] [PDF] [Supplemental Methods, Table, and Figures]   The role of the polycomb complex in silencing -globin gene expression in nonerythroid cells David Garrick, Marco De Gobbi, Vasiliki Samara, Michelle Rugless, Michelle Holland, Helena Ayyub, Karen Lower, Jackie Sloane-Stanley, Nicki Gray, Christoph Koch, Ian Dunham, and Douglas R. Higgs Blood 2008 112: 3889-3899. Prepublished online August 8, 2008; DOI 10.1182/blood-2008-06-161901 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]   Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice M. Estela Campanella, Haiyan Chu, Nancy J. Wandersee, Luanne L. Peters, Narla Mohandas, Diana M. Gilligan, and Philip S. Low Blood 2008 112: 3900-3906. Prepublished online August 12, 2008; DOI 10.1182/blood-2008-03-146159 [Abstract] [Full Text] [PDF] [Supplemental Figures]   TRANSPLANTATION: Cognitive and behavioral abnormalities in children after hematopoietic stem cell transplantation for severe congenital immunodeficiencies Penny Titman, Elizabeth Pink, Emily Skucek, Katherine O'Hanlon, Tim J. Cole, Jane Gaspar, JinHua Xu-Bayford, Alison Jones, Adrian J. Thrasher, E. Graham Davies, Paul A. Veys, and H. Bobby Gaspar Blood 2008 112: 3907-3913. Prepublished online July 21, 2008; DOI 10.1182/blood-2008-04-151332 [Abstract] [Full Text] [PDF] [Supplemental Tables]   CORRESPONDENCE: Long-term follow-up results of IFM99-03 and IFM99-04 trials comparing nonmyeloablative allotransplantation with autologous transplantation in high-risk de novo multiple myeloma Philippe Moreau, Frédéric Garban, Michel Attal, Mauricette Michallet, Gérald Marit, Cyrille Hulin, Lotfi Benboubker, Chantal Doyen, Mohamad Mohty, Ibrahim Yakoub-Agha, Serge Leyvraz, Philippe Casassus, Hervé Avet-Loiseau, Laurent Garderet, Claire Mathiot, and Jean-Luc Harousseau, on behalf of the IFM group Blood 2008 112: 3914-3915. [Full Text] [PDF]   To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

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